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Selected Publications

Mar 2005  Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease (Nature Genetics)

May 2007  FCGR3B copy number variation is associated with susceptibility to systemic but not organ-specific autoimmunity  (Nature Genetics)

Apr 2008  Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass (Nature Genetics)

Jan 2009  Repeatability of published microarray gene expression analyses (Nature Genetics)

Sep 2010  A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk (Nature)

Oct 2011  Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function (Nature)

Feb 2013  Expression profiling of subplate reveals a spatially and temporally dynamic gene network and disease association with autism and schizophrenia (PNAS)

Aug 2014  Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease (Cell Reports)

Jan 2015  Systems-Genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus    (Nature Communications)

Mar 2015 EvoTol: A protein-sequence based evolutionary intolerance framework for disease-gene prioritization (Nucleic Acids Research)


Feb 2016  Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease (Nature Neuroscience)


Dec 2016 Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery (Genome Biology)


Mar 2017 Genome-wide analysis of differential RNA editing in epilepsy (Genome Research)

Sep 2017  Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants                      (Nature Communications)

Jan 2018  Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk (Annals of the Rheumatic Diseases)

Sep 2018  A systems-level framework for drug discovery identifies Csf1r as an anti-epileptic drug target  (Nature Communications)

Aug 2019  WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signalling (Nature Communications)

Nov 2019  A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation (Nature Neuroscience)

Feb 2020  Whole-genome sequencing of Finnish type 1 diabetic siblings discordant for kidney disease reveals DNA variants associated with diabetic nephropathy (JASN)

Oct 2020  EpiMogrify Models H3K4me3 Data to Identify Signaling Molecules that Improve Cell Fate Control and Maintenance                  (Cell Systems)

Oct 2020  Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation (Genome Medicine)


Nov 2020  Brugada syndrome genetics is associated with phenotype severity (European Heart Journal)

- Friedrich Nietzsche -

“We hear only those questions for which we are in a position to find answers


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